A recent study reveals that unclassified bacteria in the Bacteroidales family may be linked to bowel cancer.
Cancer has become increasingly common in recent years and medical scientists are not closer to a permanent cure or vaccine for cancer. However, cancer research is still devoted to studying the disease to find the cause, prevention, and cure. Recently, a study on bowel cancer revealed that individuals who have a specific type of bacteria in their bowel are more predisposed to cancer of the bowel than those who do not have it.
A Review of the Bowel Cancer Study
Several organs in the human body have a collection of bacteria, fungi and viruses called the microbiome. This microbiome plays a key role in an individual’s susceptibility to disease. One of the researchers, Kaitlin Wade, said that people with Bacteroidales in their gut are at a higher risk of developing bowel cancer than those who don’t have it. This Bacteroidales are unclassified bacteria that increase the risk of bowel cancer by 2% to 15%.
The research was conducted using the Mendelian Randomisation method which is used to find the cause of a disease by identifying the roles bacteria play in the organ. They identified random inherited variations in people’s genes. This revealed that people with a certain type of genetic makeup are at higher risk of colorectal cancer.
The study involved data from 12,328 participants of the international Genetics and Epidemiology of Colorectal Cancer Consortium and 3,890 people from other studies that required bowel sampling. This way, they didn’t need to directly edit anybody’s microbiome or waste time waiting for a group of random people to get bowel cancer.
While the study revealed that the presence of Bacteroidales in the bowel can increase the risk of developing bowel cancer, it didn’t state that manipulating this bacteria reduces the risk. Perhaps future studies will need to be conducted in this regard.