Research underway to assess efficacy of mix & match coronavirus jabs

Research underway to assess efficacy of mix & match coronavirus jabs

by Pranali Mehta

In the United Kingdom, four distinct Covid-19 vaccines have been approved, with additional awaiting approval. Typically, two doses of the same vaccination are given to the people, however research is underway to assess whether administering a second dosage of an alternate Covid-19 vaccine could result in a more powerful immune response among people.

According to sources, several UK ministers are contemplating giving out an additional shot of a different vaccine to people this autumn to guard them against variants that are somewhat resistant to existing vaccines.

The possible use of Oxford, Moderna, Novavax, and BioNTech vaccines is being investigated in the United Kingdom as part of a research, which began earlier this year. Separate trials in Spain and Germany reportedly yielded promising results.

According to findings from a study conducted on less than 30 people aged between 25 and 46, participants who were administered with the combined vaccine regime almost had four-times higher median neutralizing antibody levels against the Alpha variant, which was first discovered in Kent, approximately two weeks following their second jab.

Neutralising antibodies against the Beta variant, which was first encountered in South Africa, were found to be lower than those against the Alpha variant in these people. These neutralizing antibodies resembled the ones first located in India. However, they were still found to be higher than in those who received two doses of the Pfizer vaccine.

According to reports, the multiple technologies used in the shots influenced the immune system to be exposed with the same target in a little different way, resulting in a more diversified immunological response.

Prof. Deenan Pillay, a virology specialist at University College London, said the technique provided greater flexibility globally. Pillay added that, results are still pending, but it spells good news that vaccine booster doses are not restricted by the supply of a single vaccine and in the future would also help administer third booster dosages.

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Pranali Mehta

A chemical engineer by qualification, Pranali Mehta dutifully walked down the slated path and worked in a chemical firm for a year. Her passion for writing however, pushed her into experimenting with the same as a career. With over three years of experience in content writ Read more...